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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TP53RK All Species: 11.52
Human Site: S34 Identified Species: 23.03
UniProt: Q96S44 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96S44 NP_291028.3 253 28160 S34 E R S S R F L S G L E L V K Q
Chimpanzee Pan troglodytes XP_514697 253 28128 S34 E R S S R F L S G L E L V K Q
Rhesus Macaque Macaca mulatta XP_001107480 201 22218 V18 L L F V S S S V E T A L T G L
Dog Lupus familis XP_853966 302 33650 S83 E R N G R F L S G L E L V K Q
Cat Felis silvestris
Mouse Mus musculus Q99PW4 244 27375 A34 L E L V Q Q G A E A R V F R G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425703 314 33606 P95 E A P P P A L P G L Q L V Q Q
Frog Xenopus laevis NP_001089506 237 26742 Y32 Q G A E A R V Y R G R F L G K
Zebra Danio Brachydanio rerio NP_001018386 231 26056 R31 G A E A R V Y R S T F L G R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647948 224 25346 E28 G E A C L I K E R F V K K Y R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002300825 226 25241 F28 A R V F E S S F V G R R S I V
Maize Zea mays NP_001146448 226 25230 F28 G R V F A S T F V G R K C V I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53323 261 29918 T34 E A I V F T T T T H P Y L P R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 68.3 78.4 N.A. 83.7 N.A. N.A. N.A. 56.3 66 61.2 N.A. 41.5 N.A. N.A. N.A.
Protein Similarity: 100 100 71.9 81.1 N.A. 88.9 N.A. N.A. N.A. 66.2 78.2 77.4 N.A. 56.9 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 86.6 N.A. 0 N.A. N.A. N.A. 46.6 0 13.3 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 6.6 93.3 N.A. 26.6 N.A. N.A. N.A. 60 33.3 26.6 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: 44.2 41.9 N.A. N.A. 32.1 N.A.
Protein Similarity: 60.4 58.1 N.A. N.A. 48.6 N.A.
P-Site Identity: 6.6 6.6 N.A. N.A. 6.6 N.A.
P-Site Similarity: 6.6 6.6 N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 25 17 9 17 9 0 9 0 9 9 0 0 0 0 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 42 17 9 9 9 0 0 9 17 0 25 0 0 0 0 % E
% Phe: 0 0 9 17 9 25 0 17 0 9 9 9 9 0 0 % F
% Gly: 25 9 0 9 0 0 9 0 34 25 0 0 9 17 9 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 9 0 0 0 0 0 0 0 9 9 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 0 17 9 25 9 % K
% Leu: 17 9 9 0 9 0 34 0 0 34 0 50 17 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 9 9 0 0 9 0 0 9 0 0 9 0 % P
% Gln: 9 0 0 0 9 9 0 0 0 0 9 0 0 9 34 % Q
% Arg: 0 42 0 0 34 9 0 9 17 0 34 9 0 17 17 % R
% Ser: 0 0 17 17 9 25 17 25 9 0 0 0 9 0 9 % S
% Thr: 0 0 0 0 0 9 17 9 9 17 0 0 9 0 0 % T
% Val: 0 0 17 25 0 9 9 9 17 0 9 9 34 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 9 0 0 0 9 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _